N-Acylethanolamines in human reproductive fluids.

@article{Schuel2002NAcylethanolaminesIH,
  title={N-Acylethanolamines in human reproductive fluids.},
  author={Herbert Schuel and Lani Johnson Burkman and Jack Lippes and Kent Crickard and Ellyn Forester and Daniele Piomelli and Andrea Giuffrida},
  journal={Chemistry and physics of lipids},
  year={2002},
  volume={121 1-2},
  pages={211-27}
}
N-Acylethanolamines (NAEs) are an important family of lipid-signaling molecules. Arachidonylethanolamide (anandamide) (AEA), palmitoylethanolamide (PEA), and oleoylethanolamide (OEA) are co-produced from similar phospholipid precursors when neurons are stimulated. AEA is an endogenous agonist (endocannabinoid) for cannabinoid receptors. It binds with higher affinity to type CB1 than to type CB2 cannabinoid receptors. PEA does not bind to CB1, while the hypothesis that it reacts with putative… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 69 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 162 references

Critical role of the endogenous cannabinoid system in mouse pup suckling and growth

E. Fride, Y. Ginsburg, +3 authors R. Mechoulam
Eur. J. Pharmacol. 419, • 2001
View 6 Excerpts
Highly Influenced

Mast cells express a peripheral cannabinoid receptor with differential sensitivity to anandamide and palmitoylethanolamide.

Proceedings of the National Academy of Sciences of the United States of America • 1995
View 9 Excerpts
Highly Influenced

Dysregulated cannabinoid signaling disrupts uterine receptivity for embryo implantation.

The Journal of biological chemistry • 2001
View 5 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…