N-Acetyltransferase-2 (NAT2) genotype frequency among Jordanian volunteers.

  title={N-Acetyltransferase-2 (NAT2) genotype frequency among Jordanian volunteers.},
  author={Yazun Bashir Jarrar and Somaia Muhammad Ismail and Yacoub M. Irshaid},
  journal={International journal of clinical pharmacology and therapeutics},
  volume={48 10},
OBJECTIVE To determine the frequency of major NAT2 alleles and genotypes among the Jordanian population. METHODS DNA samples from 150 healthy Jordanian volunteers were analyzed by polymerase chain reaction followed by restriction fragment length polymorphism assays (PCR-RFLP) to determine the frequency of four major alleles: NAT2*4, NAT2*5, NAT2*6 and NAT2*7. RESULTS The frequency (95% confidence interval) of NAT2*4, NAT2*5, NAT2*6 and NAT2*7 alleles was 0.247 (0.198 - 0.296), 0.373 (0.318… CONTINUE READING