N-α-PGP and PGP, potential biomarkers and therapeutic targets for COPD

@article{OReilly2009NPGPAP,
  title={N-α-PGP and PGP, potential biomarkers and therapeutic targets for COPD},
  author={Philip J. O'Reilly and Patricia L. Jackson and Brett D. Noerager and Suzanne H. Parker and Mark Thomas Dransfield and Amit Gaggar and J Edwin Blalock},
  journal={Respiratory Research},
  year={2009},
  volume={10},
  pages={38 - 38}
}
BackgroundChronic obstructive pulmonary disease (COPD) is a common respiratory disorder for which new diagnostic and therapeutic approaches are required. Hallmarks of COPD are matrix destruction and neutrophilic airway inflammation in the lung. We have previously described two tri-peptides, N-α-PGP and PGP, which are collagen fragments and neutrophil chemoattractants. In this study, we investigate if N-α-PGP and PGP are biomarkers and potential therapeutic targets for COPD.MethodsInduced sputum… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 37 REFERENCES

Induction of lung emphysema is prevented by L-arginine-threonine-arginine.

  • FASEB journal : official publication of the Federation of American Societies for Experimental Biology
  • 2008
VIEW 2 EXCERPTS

Potential role of high-mobility group box 1 in cystic fibrosis airway disease.

  • American journal of respiratory and critical care medicine
  • 2008
VIEW 2 EXCERPTS