N,N,N-Trimethylchitosan chloride as a gene vector: synthesis and application.

Abstract

N,N,N-Trimethylchitosan chloride with different degrees of quaternization has been synthesized and characterized by (1)H NMR spectroscopy. The particle size ranges from 150 to 600 nm, which is dependent on the N/P ratio and is less influenced by the degree of quaternization. The majority of the particles have a spherical morphology. The zeta potential of… (More)

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