N(carboxymethyl)lysine as a biomarker for microvascular complications in type 2 diabetic patients.

@article{Wautier2003NcarboxymethyllysineAA,
  title={N(carboxymethyl)lysine as a biomarker for microvascular complications in type 2 diabetic patients.},
  author={M. P. Wautier and Pascale Massin and P. J. Guillausseau and Maya S P Huijberts and Brian Levy and Eric Boulanger and Marie Laloi-Michelin and J L Wautier},
  journal={Diabetes & metabolism},
  year={2003},
  volume={29 1},
  pages={44-52}
}
AIMS Hyperglycemia is linked to vascular dysfunction in patients with diabetes mellitus, either directly or through advanced glycation end product (AGE) formation. Experimental evidence has indicated the possible involvement of AGEs in the genesis of vascular complications. We investigated whether serum levels of AGEs and of the glycoxidation compound carboxymethyl-lysine (CML) were increased and correlated with vascular complications in type II diabetes mellitus. METHODS Serum levels of AGEs… CONTINUE READING
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