Myxoid liposarcoma with EWS-CHOP type 1 fusion gene.

  title={Myxoid liposarcoma with EWS-CHOP type 1 fusion gene.},
  author={Kayo Suzuki and Yoshito Matsui and Kenji Endo and Takahiro Kubo and Tadashi Hasegawa and Tomoatsu Kimura and Osamu Ohtani and Natsuo Yasui},
  journal={Anticancer research},
  volume={30 11},
BACKGROUND In myxoid liposarcoma (MLS), the t(12;16)(q13;p11) chromosomal translocation and its resultant fusion transcript, the human translocation liposarcoma (TLS)-CCAAT/enhancer binding protein (C/EBP) homologous protein (CHOP), are found in the majority of cases. On the other hand, the variant translocation, t(12;22)(q13;q12) creating the Ewing sarcoma (EWS)-CHOP fusion transcript, is detectable in a limited number of cases. PATIENTS AND METHODS Tissue from MLS arising in the left thigh… CONTINUE READING