Myths, reality and future of mesenchymal stem cell therapy

  title={Myths, reality and future of mesenchymal stem cell therapy},
  author={Rimma A. Poltavtseva and A. V. Poltavtsev and Gennady V. Lutsenko and Elena V. Svirshchevskaya},
  journal={Cell and Tissue Research},
Mesenchymal stem cell (MSC) therapy represents an alternative approach for tissue regeneration and inflammation control. In spite of a huge amount of preclinical data that has been accumulated on the therapeutic properties of MSCs, there are many conflicting results, possibly due to differences in the properties of MSCs obtained from different sources or underestimated mechanisms of MSC in vivo behavior. This review consolidates the in vivo effects of MSC therapy, discusses the fate of MSCs…