Mysteries of muscle contraction.

@article{Herzog2008MysteriesOM,
  title={Mysteries of muscle contraction.},
  author={Walter Herzog and Timothy R. Leonard and Venus Joumaa and Ashi Mehta},
  journal={Journal of applied biomechanics},
  year={2008},
  volume={24 1},
  pages={1-13}
}
According to the cross-bridge theory, the steady-state isometric force of a muscle is given by the amount of actin-myosin filament overlap. However, it has been known for more than half a century that steady-state forces depend crucially on contractile history. Here, we examine history-dependent steady-state force production in view of the cross-bridge theory, available experimental evidence, and existing explanations for this phenomenon. This is done on various structural levels, ranging from… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 22 extracted citations

A multisegmental cross-bridge kinetics model of the myofibril.

Journal of theoretical biology • 2009
View 5 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 37 references

Active tension generation in isolated skeletal myofibrils

Journal of Muscle Research & Cell Motility • 1993
View 5 Excerpts
Highly Influenced

Muscle structure and theories of contraction.

Progress in biophysics and biophysical chemistry • 1957
View 6 Excerpts
Highly Influenced

The mechanics of active muscle

A. V. Hill
Proceedings of the Royal Society London, • 1953
View 4 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…