Myristoylation of the arterivirus E protein: the fatty acid modification is not essential for membrane association but contributes significantly to virus infectivity.

@article{Thaa2009MyristoylationOT,
  title={Myristoylation of the arterivirus E protein: the fatty acid modification is not essential for membrane association but contributes significantly to virus infectivity.},
  author={Bastian Thaa and Aleksander Kabatek and Jessika C. Zevenhoven-Dobbe and Eric J. Snijder and Andreas Herrmann and Michael Veit},
  journal={The Journal of general virology},
  year={2009},
  volume={90 Pt 11},
  pages={2704-12}
}
The envelope of equine arteritis virus (EAV) contains two glycoprotein complexes (GP2b/GP3/GP4 and GP5/M) and the small, non-glycosylated E protein. As E is essential for the production of infectious progeny but dispensable for assembly and release of virus-like particles, it probably mediates virus entry into cells, putatively in concert with the GP2b/GP3/GP4 complex. The E protein contains a central hydrophobic domain and a conserved potential site for N-terminal myristoylation, a hydrophobic… CONTINUE READING