Myristoyl moiety of HIV Nef is involved in regulation of the interaction with calmodulin in vivo.

Abstract

Human immunodeficiency virus Nef is a myristoylated protein expressed early in infection by HIV. In addition to the well known down-regulation of the cell surface receptors CD4 and MHCI, Nef is able to alter T-cell signaling pathways. The ability to alter the cellular signaling pathways suggests that Nef can associate with signaling proteins. In the present… (More)

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Cite this paper

@article{Matsubara2005MyristoylMO, title={Myristoyl moiety of HIV Nef is involved in regulation of the interaction with calmodulin in vivo.}, author={Mamoru Matsubara and Tao Jing and Kumi Kawamura and Naoshi Shimojo and Koiti Titani and Keiichiro Hashimoto and Nobuhiro Hayashi}, journal={Protein science : a publication of the Protein Society}, year={2005}, volume={14 2}, pages={494-503} }