Myostatin mutation associated with gross muscle hypertrophy in a child.

  title={Myostatin mutation associated with gross muscle hypertrophy in a child.},
  author={M. Schuelke and K. Wagner and L. E. Stolz and C. H{\"u}bner and T. Riebel and Wolfgang K{\"o}men and T. Braun and J. Tobin and S. Lee},
  journal={The New England journal of medicine},
  volume={350 26},
  • M. Schuelke, K. Wagner, +6 authors S. Lee
  • Published 2004
  • Medicine
  • The New England journal of medicine
  • Both acquired and inherited disorders of muscle are common; thus, greater understanding of muscle growth and maintenance is important for future therapies. Myostatin down-regulates muscle growth. These investigators describe a mutation in the gene for myostatin in a child with muscle hypertrophy and unusual strength. 
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