Myostatin inhibition induces muscle fibre hypertrophy prior to satellite cell activation.

Abstract

Muscle fibres are multinucleated post-mitotic cells that can change dramatically in size during adulthood. It has been debated whether muscle fibre hypertrophy requires activation and fusion of muscle stem cells, the satellite cells. Myostatin (MSTN) is a negative regulator of skeletal muscle growth during development and in the adult, and MSTN inhibition… (More)
DOI: 10.1113/jphysiol.2011.226001

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Cite this paper

@article{Wang2012MyostatinII, title={Myostatin inhibition induces muscle fibre hypertrophy prior to satellite cell activation.}, author={Qian Wang and Alexandra C. McPherron}, journal={The Journal of physiology}, year={2012}, volume={590 9}, pages={2151-65} }