Myositis: Are autoantibodies pathogenic in necrotizing myopathy?

@article{Dalakas2018MyositisAA,
  title={Myositis: Are autoantibodies pathogenic in necrotizing myopathy?},
  author={M. Dalakas},
  journal={Nature Reviews Rheumatology},
  year={2018},
  volume={14},
  pages={251-252}
}
  • M. Dalakas
  • Published 2018
  • Medicine
  • Nature Reviews Rheumatology
  • What causes muscle fibre necrosis in necrotizing myopathy? The authors of a new study propose that specific autoantibodies contribute to disease via immune-mediated processes; but given that these processes also occur in muscular dystrophies, how likely is that these antibodies trigger muscle fibre necrosis? 
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