Myosins II and V in chromaffin cells: myosin V is a chromaffin vesicle molecular motor involved in secretion.

@article{Ros2003MyosinsIA,
  title={Myosins II and V in chromaffin cells: myosin V is a chromaffin vesicle molecular motor involved in secretion.},
  author={Sergio D Ros{\'e} and Tatiana Lejen and Luciana Casaletti and Roy Edward Larson and Teodora Dumitrescu Pene and J. M. Trifar{\'o}},
  journal={Journal of neurochemistry},
  year={2003},
  volume={85 2},
  pages={287-98}
}
The presence of myosin II and V in chromaffin cells and their subcellular distribution is described. Myosin II and V distribution in sucrose density gradients showed only a strong correlation between the distribution of myosin V and secretory vesicle markers. Confocal microscopy images demonstrated colocalization of myosin V with dopamine beta-hydroxylase, a chromaffin vesicle marker, whereas myosin II was present mainly in the cell cortex. Cell depolarization induced, in a Ca2+ and time… CONTINUE READING
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