Myosin-X is critical for migratory ability of Xenopus cranial neural crest cells.

@article{Nie2009MyosinXIC,
  title={Myosin-X is critical for migratory ability of Xenopus cranial neural crest cells.},
  author={Shuyi Nie and Yun Kee and Marianne Bronner-Fraser},
  journal={Developmental biology},
  year={2009},
  volume={335 1},
  pages={132-42}
}
The neural crest is a highly migratory cell population, unique to vertebrates, that forms much of the craniofacial skeleton and peripheral nervous system. In exploring the cell biological basis underlying this behavior, we have identified an unconventional myosin, myosin-X (Myo10) that is required for neural crest migration. Myo10 is highly expressed in both premigratory and migrating cranial neural crest (CNC) cells in Xenopus embryos. Disrupting Myo10 expression using antisense morpholino… CONTINUE READING