Myosin-X is an unconventional myosin that undergoes intrafilopodial motility

@article{Berg2002MyosinXIA,
  title={Myosin-X is an unconventional myosin that undergoes intrafilopodial motility},
  author={Jonathan S. Berg and Richard E. Cheney},
  journal={Nature Cell Biology},
  year={2002},
  volume={4},
  pages={246-250}
}
Filopodia are thin cellular protrusions that are important in cell motility and neuronal growth cone guidance. The actin filaments that make up the core of a filopodium undergo continuous retrograde flow towards the cell body. Surface receptors or particles can couple to this retrograde flow and can also move forward to the tips of filopodia, although the molecular basis of forward transport is unknown. We report here that myosin-X (Myo10 or M10), the founding member of a novel class of myosins… 

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