Myosin VI is differentially regulated by DNA damage in p53- and cell type-dependent manners.

@article{Cho2010MyosinVI,
  title={Myosin VI is differentially regulated by DNA damage in p53- and cell type-dependent manners.},
  author={Seong Jun Cho and Xinbin Chen},
  journal={The Journal of biological chemistry},
  year={2010},
  volume={285 35},
  pages={27159-66}
}
Myosin VI is an unconventional motor protein and functions in a variety of intracellular processes such as cell migration, vesicular trafficking, and homeostasis of the Golgi complex. Previously, we found that myosin VI is up-regulated in RKO, LS174T, and H1299 cells by DNA damage in a p53-dependent manner and mediates the pro-survival function of p53. Here… CONTINUE READING