Myosin V-mediated vacuole distribution and fusion in fission yeast

@article{Mulvihill2001MyosinVV,
  title={Myosin V-mediated vacuole distribution and fusion in fission yeast},
  author={Daniel P Mulvihill and Patrick J. Pollard and Thein Z Win and Jeremy S. Hyams},
  journal={Current Biology},
  year={2001},
  volume={11},
  pages={1124-1127}
}
The class V myosins are actin-based motors that move a variety of cellular cargoes [1]. In budding yeast, their activity includes the relocation of a portion of the vacuole from the mother cell to the bud [2, 3]. Fission yeast cells contain numerous (approximately 80) small vacuoles. When S. pombe cells are placed in water, vacuoles fuse in response to osmotic stress [4]. Fission yeast possess two type V myosin genes, myo51(+) and myo52(+) [5]. In a myo51Delta strain, vacuoles were distributed… CONTINUE READING