Myosin-V is a processive actin-based motor

@article{Mehta1999MyosinVIA,
  title={Myosin-V is a processive actin-based motor},
  author={Amit D. Mehta and Ronald S Rock and Matthias Rief and James A. Spudich and Mark S. Mooseker and Richard E. Cheney},
  journal={Nature},
  year={1999},
  volume={400},
  pages={590-593}
}
Class-V myosins, one of 15 known classes of actin-based molecular motors, have been implicated in several forms of organelle transport perhaps working with microtubule-based motors such as kinesin,. Such movements may require a motor with mechanochemical properties distinct from those of myosin-II, which operates in large ensembles to drive high-speed motility as in muscle contraction. Based on its function and biochemistry, it has been suggested that myosin-V may be a processive motor, like… Expand
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  • D. Smith
  • Chemistry, Medicine
  • Journal of Muscle Research & Cell Motility
  • 2004
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