Myosin V attachment to cargo requires the tight association of two functional subdomains

Abstract

The myosin V carboxyl-terminal globular tail domain is essential for the attachment of myosin V to all known cargoes. Previously, the globular tail was viewed as a single, functional entity. Here, we show that the globular tail of the yeast myosin Va homologue, Myo2p, contains two structural subdomains that have distinct functions, namely, vacuole-specific… (More)

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Cite this paper

@article{Pashkova2005MyosinVA, title={Myosin V attachment to cargo requires the tight association of two functional subdomains}, author={Natasha Pashkova and Natalie L. Catlett and Jennifer L. Novak and Guanming Wu and Renne Chen Lu and Robert E Cohen and Lois S Weisman}, journal={The Journal of Cell Biology}, year={2005}, volume={168}, pages={359 - 364} }