Myosin II dynamics are regulated by tension in intercalating cells.

  title={Myosin II dynamics are regulated by tension in intercalating cells.},
  author={Rodrigo Fernandez-Gonzalez and S{\'e}rgio de Matos Sim{\~o}es and Jens-Christian R{\"o}per and Suzanne Eaton and Jennifer A Zallen},
  journal={Developmental cell},
  volume={17 5},
Axis elongation in Drosophila occurs through polarized cell rearrangements driven by actomyosin contractility. Myosin II promotes neighbor exchange through the contraction of single cell boundaries, while the contraction of myosin II structures spanning multiple pairs of cells leads to rosette formation. Here we show that multicellular actomyosin cables form at a higher frequency than expected by chance, indicating that cable assembly is an active process. Multicellular cables are sites of… CONTINUE READING
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