Myosin-1c, the hair cell's adaptation motor.

  title={Myosin-1c, the hair cell's adaptation motor.},
  author={Peter G. Gillespie and Janet L. Cyr},
  journal={Annual review of physiology},
Given their prominent actin-rich subcellular specializations, it is no surprise that mechanosensitive hair cells of the inner ear exploit myosin molecules-the only known actin-dependent molecular motors-to carry out exotic but essential tasks. Recent experiments have confirmed that an unconventional myosin isozyme, myosin-1c, is a component of the hair cell's adaptation-motor complex. This complex carries out slow adaptation, provides tension to sensitize transduction channels, and may… CONTINUE READING

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