Myoinositol abnormalities in temporal lobe epilepsy.

  title={Myoinositol abnormalities in temporal lobe epilepsy.},
  author={R. Mark Wellard and Regula S. Briellmann and James W. Prichard and Ari Syngeniotis and Graeme D. Jackson},
  volume={44 6},
PURPOSE This study used magnetic resonance spectroscopy (MRS) to examine metabolite abnormalities in the temporal and frontal lobe of patients with temporal lobe epilepsy (TLE) of differing severity. METHODS We investigated myoinositol in TLE by using short-echo MRS in 34 TLE patients [26 late onset (LO-TLE), eight hippocampal sclerosis (HS-TLE)], and 16 controls. Single-voxel short-echo (35 ms) MR spectra of temporal and frontal lobes were acquired at 1.5 T and analyzed by using LCModel… CONTINUE READING


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