Myoinositol: The Bridge (PONTI) to Reach a Healthy Pregnancy

  title={Myoinositol: The Bridge (PONTI) to Reach a Healthy Pregnancy},
  author={Pietro Cavalli and Elena Ronda},
  booktitle={International journal of endocrinology},
The use of folic acid in the periconceptional period can prevent about 70% of neural tube defects (NTDs). In the remaining cases, no medical prevention is available, and those conditions should be defined as folate-resistant NTDs. Rodent models suggest that some folate-resistant NTDs can be prevented by inositol (myoinositol and chiroinositol) supplementation prior to pregnancy. Should folic acid be combined with myoinositol periconceptional supplementation to reduce the overall risk of NTDs… CONTINUE READING