Myogenic specification of side population cells in skeletal muscle

  title={Myogenic specification of side population cells in skeletal muscle},
  author={Atsushi Asakura and Patrick Seale and Adele A Girgis-Gabardo and Michael Rudnicki},
  journal={The Journal of Cell Biology},
  pages={123 - 134}
Skeletal muscle contains myogenic progenitors called satellite cells and muscle-derived stem cells that have been suggested to be pluripotent. We further investigated the differentiation potential of muscle-derived stem cells and satellite cells to elucidate relationships between these two populations of cells. FACS(R) analysis of muscle side population (SP) cells, a fraction of muscle-derived stem cells, revealed expression of hematopoietic stem cell marker Sca-1 but did not reveal expression… CONTINUE READING
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