Myogenic regulatory factors and the specification of muscle progenitors in vertebrate embryos.

@article{Pownall2002MyogenicRF,
  title={Myogenic regulatory factors and the specification of muscle progenitors in vertebrate embryos.},
  author={Mary E Pownall and Marcus K Gustafsson and Charles Phillips Emerson},
  journal={Annual review of cell and developmental biology},
  year={2002},
  volume={18},
  pages={
          747-83
        }
}
Embryological and genetic studies of mouse, bird, zebrafish, and frog embryos are providing new insights into the regulatory functions of the myogenic regulatory factors, MyoD, Myf5, Myogenin, and MRF4, and the transcriptional and signaling mechanisms that control their expression during the specification and differentiation of muscle progenitors. Myf5 and MyoD genes have genetically redundant, but developmentally distinct regulatory functions in the specification and the differentiation of… CONTINUE READING

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