Myogenic regulatory factors and the specification of muscle progenitors in vertebrate embryos.

  title={Myogenic regulatory factors and the specification of muscle progenitors in vertebrate embryos.},
  author={M. Pownall and M. Gustafsson and C. Emerson},
  journal={Annual review of cell and developmental biology},
  • M. Pownall, M. Gustafsson, C. Emerson
  • Published 2002
  • Biology, Medicine
  • Annual review of cell and developmental biology
  • Embryological and genetic studies of mouse, bird, zebrafish, and frog embryos are providing new insights into the regulatory functions of the myogenic regulatory factors, MyoD, Myf5, Myogenin, and MRF4, and the transcriptional and signaling mechanisms that control their expression during the specification and differentiation of muscle progenitors. Myf5 and MyoD genes have genetically redundant, but developmentally distinct regulatory functions in the specification and the differentiation of… CONTINUE READING
    519 Citations

    Topics from this paper.

    Myf5 expression during fetal myogenesis defines the developmental progenitors of adult satellite cells.
    • 50
    • Highly Influenced
    Expression of myogenic regulatory factors in chicken embryos during somite and limb development
    • 18
    • PDF
    Activation of RXR and RAR signaling promotes myogenic differentiation of myoblastic C2C12 cells.
    • 75
    An analysis of MyoD-dependent transcription using CRISPR/Cas9 gene targeting in Xenopus tropicalis embryos
    • 5
    Myogenic waves and myogenic programs during Xenopus embryonic myogenesis
    • 19
    • Highly Influenced
    Smarcd3 Regulates the Timing of Zebrafish Myogenesis Onset*
    • 22
    • PDF
    Genetic analysis of interactions between the somitic muscle, cartilage and tendon cell lineages during mouse development
    • 136
    • Highly Influenced
    • PDF
    Two cell lineages, myf5 and myf5-independent, participate in mouse skeletal myogenesis.
    • 127
    • PDF


    Pax3 functions in cell survival and in pax7 regulation.
    • 192
    Ectopic expression of MyoD1 in mice causes prenatal lethalities
    • 21