Myocyte necrosis is the basis for fibrosis in renovascular hypertensive rats.

@article{Okoshi1997MyocyteNI,
  title={Myocyte necrosis is the basis for fibrosis in renovascular hypertensive rats.},
  author={Marina Politi Okoshi and Luiz Shiguero Matsubara and Martha Franco and Ant{\^o}nio Carlos Cicogna and Beatriz Bojikian Matsubara},
  journal={Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas},
  year={1997},
  volume={30 9},
  pages={1135-44}
}
The pathogenesis of fibrosis and the functional features of pressure overload myocardial hypertrophy are still controversial. The objectives of the present study were to evaluate the function and morphology of the hypertrophied myocardium in renovascular hypertensive (RHT) rats. Male Wistar rats were sacrificed at week 4 (RHT4) and 8 (RHT8) after unilateral renal ischemia (Goldblatt II hypertension model). Normotensive rats were used as controls. Myocardial function was analyzed in isolated… CONTINUE READING
18 Citations
38 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 18 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 38 references

Similar Papers

Loading similar papers…