Myoclonus: current concepts and recent advances.

  title={Myoclonus: current concepts and recent advances.},
  author={John N. Caviness and Peter Brown},
  journal={The Lancet. Neurology},
  volume={3 10},
Myoclonus presents as a sudden brief jerk caused by involuntary muscle activity. An organisational framework is crucial for determining the medical significance of the myoclonus as well as for its treatment. Clinical presentations of myoclonus are divided into physiological, essential, epileptic, and symptomatic. Most causes of myoclonus are symptomatic and include posthypoxia, toxic-metabolic disorders, reactions to drugs, storage disease, and neurodegenerative disorders. The assessment of… CONTINUE READING
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