Myoclonic disorders: a practical approach for diagnosis and treatment.

  title={Myoclonic disorders: a practical approach for diagnosis and treatment.},
  author={Maja Kojovi{\'c} and Carla Cordivari and Kailash P Bhatia},
  journal={Therapeutic advances in neurological disorders},
  volume={4 1},
Myoclonus is a sudden, brief, involuntary muscle jerk. It is caused by abrupt muscle contraction, in the case of positive myoclonus, or by sudden cessation of ongoing muscular activity, in the case of negative myoclonus (NM). Myoclonus may be classified in a number of ways, although classification based on the underlying physiology is the most useful from the therapeutic viewpoint. Given the large number of possible causes of myoclonus, it is essential to take a good history, to clinically… CONTINUE READING
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