Myocet (liposome-encapsulated doxorubicin citrate): a new approach in breast cancer therapy

@article{Batist2002MyocetD,
  title={Myocet (liposome-encapsulated doxorubicin citrate): a new approach in breast cancer therapy},
  author={Gerald Batist and Jeremy Barton and Philip Chaikin and Christine E. Swenson and Lauri Welles},
  journal={Expert Opinion on Pharmacotherapy},
  year={2002},
  volume={3},
  pages={1739 - 1751}
}
Doxorubicin, either as a single agent or in combination regimens, is considered to be one of the most active chemotherapeutic agents in the treatment of metastatic breast cancer. However, its clinical utility is limited by a cumulative, dose-dependent cardiac myopathy that can lead to potentially fatal congestive heart failure. Considerable research has gone into improving the therapeutic index of doxorubicin-based regimens. A new liposomal formulation of doxorubicin (Myocet™, Elan… 
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