Myocardial no-reflow in humans.

  title={Myocardial no-reflow in humans.},
  author={Giampaolo Niccoli and Francesco Burzotta and Leonarda Galiuto and Filippo Crea},
  journal={Journal of the American College of Cardiology},
  volume={54 4},
In a variable proportion of patients presenting with ST-segment elevation myocardial infarction, ranging from 5% to 50%, primary percutaneous coronary intervention achieves epicardial coronary artery reperfusion but not myocardial reperfusion, a condition known as no-reflow. Of note, no-reflow is associated with a worse prognosis at follow-up. The phenomenon has a multifactorial pathogenesis including: distal embolization, ischemia-reperfusion injury, and individual predisposition of coronary… CONTINUE READING
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