Myocardial markers of injury. Evolution and insights.

  title={Myocardial markers of injury. Evolution and insights.},
  author={Joseph H Keffer},
  journal={American journal of clinical pathology},
  volume={105 3},
Knowledge of the pathophysiology of ischemic heart disease has advanced in parallel with awareness of the significant limitations inherent in clinical assessment. Biochemical assays, long established as the most reliable means of detecting myocardial injury, have improved significantly. Creatine kinase MB, now optimally measured by the newer mass monoclonal antibody assays, and also measurement of the cardiac troponins objectively identify adverse prognosis. Cardiac troponin I appears to have… CONTINUE READING