Myocardial ischemia and reperfusion.

  title={Myocardial ischemia and reperfusion.},
  author={Robert B. Jennings and Charles Steenbergen and Keith A. Reimer},
  journal={Monographs in pathology},
Myocardial infarction is a dynamic process that begins with the transition from reversible to irreversible ischemic injury and culminates in the replacement of dead myocardium by a fibrous scar. Many biochemical and metabolic changes have been observed early after the onset of ischemia, but the precise cause of the transition to irreversibility has not been elucidated. However, disruption of the plasmalemma of the sarcolemma is an early event, the presence of which indicates that the ischemic… CONTINUE READING
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