Myocardial iron loading in patients with thalassemia major on deferoxamine chelation.

  title={Myocardial iron loading in patients with thalassemia major on deferoxamine chelation.},
  author={Mark A Tanner and Renzo Galanello and Carlo Dess{\`i} and Mark A. Westwood and Gill Smith and Sunil V Nair and Lisa J. Anderson and John Malcolm Walker and Dudley J. Pennell},
  journal={Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance},
  volume={8 3},
BACKGROUND Heart failure secondary to myocardial iron loading remains the leading cause of death in thalassemia major (TM). We used cardiovascular magnetic resonance (CMR) to assess the prevalence of myocardial iron overload and ventricular dysfunction in a large cohort of TM patients maintained on conventional chelation treatment with deferoxamine. METHODS A mobile CMR scanner was transported from London, UK, to Sardinia, Italy where 167 TM patients were assessed for myocardial iron loading… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 72 extracted citations

Evaluation of Iron Deposition in the Adrenal Glands of β Thalassemia Major Patients Using 3-Tesla MRI

Iranian journal of radiology : a quarterly journal published by the Iranian Radiological Society • 2016
View 2 Excerpts


Publications referenced by this paper.
Showing 1-10 of 19 references

Baseline findings of a CMR driven randomized controlled trial of iron chelation therapy in thalassemia major (abstract)

MA Tanner, MA Westwood, R Galanello, DJ. Pennell
J Cardiovasc Magn Reson 2005;7:31–2 • 2005
View 1 Excerpt

The heart in thalassaemia.

European heart journal • 2002
View 1 Excerpt

Cardiovascular T2∗ (T2 star) magnetic resonance for the early diagnosis of myocardial iron overload

LJ Anderson, S Holden, +8 authors DJ. Pennell
Eur Heart J 2001;22:2171– • 2001
View 1 Excerpt

Heart failure in beta-thalassemia.

Congestive heart failure • 2001
View 1 Excerpt

Similar Papers

Loading similar papers…