Myocardial infarction-prone Watanabe heritable hyperlipidemic rabbits with mesenteric fat accumulation are a novel animal model for metabolic syndrome.

@article{Shiomi2012MyocardialIW,
  title={Myocardial infarction-prone Watanabe heritable hyperlipidemic rabbits with mesenteric fat accumulation are a novel animal model for metabolic syndrome.},
  author={Masashi Shiomi and Tsutomu Yoshimura Hiroyuki Kobayashi and Nobue Kuniyoshi and Satoshi Yamada and Takashi Ito},
  journal={Pathobiology : journal of immunopathology, molecular and cellular biology},
  year={2012},
  volume={79 6},
  pages={
          329-38
        }
}
OBJECTIVES To examine whether the myocardial infarction-prone Watanabe heritable hyperlipidemic (WHHLMI) rabbit with visceral fat accumulation is a new animal model for human metabolic syndrome, we examined the relationship between mesenteric fat accumulation and insulin resistance, hyperlipidemia and atherosclerosis. METHODS Glucose tolerance tests were performed using adult (11- to 15-month-old) and middle-aged (17- to 21-month-old) WHHLMI rabbits fed standard chow restrictedly. In addition… CONTINUE READING

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