Myocardial imaging with a radioiodinated norepinephrine storage analog.

  title={Myocardial imaging with a radioiodinated norepinephrine storage analog.},
  author={Donald M. Wieland and Lee E Brown and W. Leslie Rogers and K C Worthington and J. L. Wu and Neal H. Clinthorne and C A Otto and Dennis P. Swanson and William H. Beierwaltes},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  volume={22 1},
Meta-iodobenzylguanidine (M-IBG), an iodinated aromatic analog of the hypotensive drug quanethidine, localizes in the heart of the rat, dog, and rhesus monkey. A comparative study of tissue distribution in the dog has been performed with five myocardiophilic agents: thallium-201, I-125 16-iodohexadecanoic acid, H-3 norepinephrine, C-14 guanethidine and I-125 M-IBG. The last two compounds give heart concentrations and heart-to-blood concentration ratios similar to those of thallium-201. Planar… CONTINUE READING


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