Myocardial gene expression of leukaemia inhibitory factor, interleukin-6 and glycoprotein 130 in end-stage human heart failure.

@article{Eiken2001MyocardialGE,
  title={Myocardial gene expression of leukaemia inhibitory factor, interleukin-6 and glycoprotein 130 in end-stage human heart failure.},
  author={H G Eiken and Erik \Oie and Jan Kristian Dam{\aa}s and Arne Yndestad and Vigdis Bjerkeli and Halfdan Aass and Svein Simonsen and Odd Ragnar Geiran and Theis T\onnessen and Geir Christensen and Stig Sophus Fr\oland and Lars Gullestad and H{\aa}vard Attramadal and P{\aa}l Aukrust},
  journal={European journal of clinical investigation},
  year={2001},
  volume={31 5},
  pages={389-97}
}
BACKGROUND Studies in different animal models and plasma analyses in humans suggest that members of the interleukin-6 (IL-6) cytokine family may be involved in the pathogenesis of congestive heart failure (CHF). Accordingly, we have examined IL-6-related cytokines in chronic CHF in humans by analysing gene and protein expression in myocardium derived from patients with end-stage heart failure and donor hearts. METHODS Gene expression of cytokines/receptors of the IL-6 family was documented in… CONTINUE READING