Myocardial gene and protein expression profiles after autoimmune injury in Chagas' disease cardiomyopathy.

@article{CunhaNeto2011MyocardialGA,
  title={Myocardial gene and protein expression profiles after autoimmune injury in Chagas' disease cardiomyopathy.},
  author={Edecio Cunha-Neto and Priscila Camillo Teixeira and Simone Gonçalves Fonseca and Angelina Morand Bianchi Bilate and Jorge Agle Kalil},
  journal={Autoimmunity reviews},
  year={2011},
  volume={10 3},
  pages={163-5}
}
One third of the 16 million of individuals infected by the protozoan Trypanosoma cruzi in Latin America eventually develop chronic Chagas' disease cardiomyopathy (CCC), an inflammatory dilated cardiomyopathy with shorter survival than non-inflammatory cardiomyopathies. The presence of a T cell-rich mononuclear inflammatory infiltrate and the relative scarcity of parasites in the heart suggested that chronic inflammation secondary to the autoimmune recognition of cardiac proteins could be a… CONTINUE READING
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Cardiac geneexpressionprofilingprovidesevidence for cytokinopathy asamolecular mechanism in Chagas' disease cardiomyopathy

  • E Cunha-Neto, VJ Dzau, PD Allen, D Satamatiou, L Benvenutti, ML Higuchi
  • Am J Pathol
  • 2005
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