Myocardial contractility in a canine model of the brain-dead organ donor.

@article{Huber1993MyocardialCI,
  title={Myocardial contractility in a canine model of the brain-dead organ donor.},
  author={Thomas Stuart Huber and Mark A. Groh and K. Egstrup. K. P. Gallagher and L G D'alecy},
  journal={Critical care medicine},
  year={1993},
  volume={21 11},
  pages={1731-9}
}
OBJECTIVE To test the hypothesis that the induction and maintenance of brain death leads to a decrease in myocardial contractility. DESIGN Prospective, randomized, controlled trial. SETTING Laboratory at a large, university-affiliated medical center. SUBJECTS Sixteen adult, male, mongrel dogs weighing 15 to 25 kg. INTERVENTIONS Myocardial contractile performance was evaluated after the induction of either brain death (n = 8), sham brain death (n = 4), or an operative procedure serving… CONTINUE READING