Myocardial collagen remodeling and left ventricular diastolic function.

  title={Myocardial collagen remodeling and left ventricular diastolic function.},
  author={Joseph S Janicki},
  journal={Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas},
  volume={25 10},
  • Joseph S Janicki
  • Published 1992 in
    Brazilian journal of medical and biological…
1. The myocardial collagen matrix is an active participant in determining ventricular architecture and diastolic function, and myocardial structural integrity and mechanical properties. It consists of a network of fibrillar collagen which is intimately related with the myocyte, myofibril and muscle fiber as well as the coronary vasculature. Consisting primarily of collagen types I and III, this material exhibits a high tensile strength which, even though normally present in relatively small… CONTINUE READING


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