Myocardial collagen metabolism in failing hearts before and during cardiac resynchronization therapy.

Abstract

BACKGROUND In patients with heart failure cardiac resynchronization therapy (CRT) leads to reverse ventricular remodelling. AIM To evaluate whether myocardial collagen metabolism in patients with heart failure is implicated in adverse ventricular remodelling and response to CRT. METHODS Collagen synthesis and degradation were assessed from the… (More)
DOI: 10.1016/j.ejheart.2008.06.019

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