Myocardial carnitine palmitoyltransferase I expression and long-chain fatty acid oxidation in fetal and newborn lambs.

@article{Bartelds2004MyocardialCP,
  title={Myocardial carnitine palmitoyltransferase I expression and long-chain fatty acid oxidation in fetal and newborn lambs.},
  author={Beatrijs Bartelds and Janny Takens and Gioia B Smid and Victor A. Zammit and Carina Prip-Buus and Jaap R G Kuipers and Feike R van der Leij},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2004},
  volume={286 6},
  pages={H2243-8}
}
Carnitine palmitoyltransferase I (CPT I) catalyzes the conversion of acyl-CoA to acylcarnitine at the outer mitochondrial membrane and is a key enzyme in the control of long-chain fatty acid (LC-FA) oxidation. Because myocardial LC-FA oxidation increases dramatically after birth, we determined the extent to which CPT I expression contributes to these changes in the perinatal lamb. We measured the steady-state level of transcripts of the CPT1A and CPT1B genes, which encode the liver (L-CPT I… CONTINUE READING
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Genomics of the human carnitine acyltransferase genes

  • FR van der Leij, NC Huijkman, C Boomsma, JR Kuipers, B. Bartelds
  • Mol Genet Metab
  • 2000
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