Myocardial capillarity in acclimation to hypoxia

  title={Myocardial capillarity in acclimation to hypoxia},
  author={Susan R. Kayar and Natalio Banchero},
  journal={Pfl{\"u}gers Archiv},
Capillarity, O2 diffusion distances and fiber crosssectional growth were measured in the hearts of guinea pigs exposed early during growth to hypobaric hypoxia (P B=430 torr,PO2=90 torr). Twelve 5-week old males were maintained in a hypobaric chamber for 4–14 weeks. Their hearts were perfusion-fixed via the aorta with a 2.5% glutaraldehyde, 1% formaldehyde buffered solution; blocks were cut from left (LV) and right (RV) ventricles, post-fixed in OsO4, dehydrated and embedded in Spurr medium… CONTINUE READING
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