Myocardial beta-adrenoceptor density one month after acute myocardial infarction predicts left ventricular volumes at six months.

@article{Spyrou2002MyocardialBD,
  title={Myocardial beta-adrenoceptor density one month after acute myocardial infarction predicts left ventricular volumes at six months.},
  author={Nicos Spyrou and Stuart D. Rosen and Farzin Fath-ordoubadi and Rohan Jagathesan and Rodney A. Foale and Jaspal Singh Kooner and Paolo G. Camici},
  journal={Journal of the American College of Cardiology},
  year={2002},
  volume={40 7},
  pages={1216-24}
}
OBJECTIVE To investigate whether myocardial beta-adrenoceptor (beta-AR) downregulation precedes and predicts left ventricular (LV) dilation after acute myocardial infarction (AMI), we measured beta-AR density within four weeks of AMI and correlated it with serial measurements of LV volumes. BACKGROUND Patients who develop heart failure following AMI have an increased sympathetic drive to the heart within the first four weeks after infarction. METHODS We prospectively studied 61 patients in… CONTINUE READING
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