Myocardial and coronary sinus purines as indicators of pig heart energy metabolism during reperfusion after extracorporeal circulation.

@article{Safranow2005MyocardialAC,
  title={Myocardial and coronary sinus purines as indicators of pig heart energy metabolism during reperfusion after extracorporeal circulation.},
  author={Krzysztof Safranow and Ryszard Rzeuski and Mariusz Listewnik and Katarzyna L. Jakubowska and Monika Ewa Ra{\'c} and Maria Joanna Olszewska and Dariusz Chlubek},
  journal={Acta physiologica Scandinavica},
  year={2005},
  volume={185 1},
  pages={13-23}
}
AIM The precise understanding of myocardial metabolism is crucial for the optimization of cardiosurgical procedures. We attempted to gain a comprehensive insight into the purine metabolism of the porcine heart during reperfusion by measuring concentrations of nucleotides, nucleosides and oxypurines simultaneously in the myocardium and coronary sinus. METHODS Twenty-five pigs were subjected to sham cardiosurgery with extracorporeal circulation and cold cardioplegic arrest of 60 min. Myocardial… CONTINUE READING