Myocardial alterations due to free-radical generation.

  title={Myocardial alterations due to free-radical generation.},
  author={Keith Burton and J M Mccord and Geetha Ghai},
  journal={The American journal of physiology},
  volume={246 6 Pt 2},
Oxygen-derived free radicals have been proposed as general mediators of tissue injury in a variety of disease states. Recent interest has focused on the possibility that free radicals may be involved in ischemic myocardial damage. However, the exact types of damage that result from myocardial exposure to free radicals remains to be established. The purpose of this study was to evaluate the effects of superoxide and hydroxyl radicals on myocardial structure and function in an isolated perfused… CONTINUE READING
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