Myocardial KATP Channels in Preconditioning

@inproceedings{ORourke2000MyocardialKC,
  title={Myocardial KATP Channels in Preconditioning},
  author={Brian O’Rourke},
  year={2000}
}
We are on the brink of harnessing the cell’s natural defenses against ischemia and reperfusion injury after years of research into the destructive and protective mechanisms involved. Since the discovery of ischemic preconditioning, the surface receptors and signal transduction pathways underlying this phenomenon have been clarified, but many questions remain about the downstream targets that ultimately protect the cell. ATP-sensitive K 1 (KATP) channels are thought to play a role in protection… CONTINUE READING

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