Myocardial Carbohydrate, Ketone, and Fatty Acid Uptake in Conscious Lambs with Aortopulmonary Shunts1

@article{Gratama1992MyocardialCK,
  title={Myocardial Carbohydrate, Ketone, and Fatty Acid Uptake in Conscious Lambs with Aortopulmonary Shunts1},
  author={J. W. Gratama and Michiel Dalinghaus and Jacobus J Meuzelaar and Alie M Gerding and Jan H Koers and Frits A. J. Muskiet and J R G Kuipers},
  journal={Pediatric Research},
  year={1992},
  volume={32},
  pages={27-32}
}
ABSTRACT: A left to right shunt increases myocardial work and is often accompanied by increased catecholamine levels. Because both increased myocardial work and increased catecholamine levels may induce increased fatty acid utilization, which could increase resting myocardial oxygen consumption and therefore unfavorably affect coronary reserve, we studied myocardial uptake of glucose, pyruvate, lactate, β-OH-butyrate, acetoacetate, FFA, and triglycerides in 12 7-wk-old lambs with aortopulmonary… CONTINUE READING