Myoblasts Derived From Normal hESCs and Dystrophic hiPSCs Efficiently Fuse With Existing Muscle Fibers Following Transplantation

@inproceedings{Goudenege2012MyoblastsDF,
  title={Myoblasts Derived From Normal hESCs and Dystrophic hiPSCs Efficiently Fuse With Existing Muscle Fibers Following Transplantation},
  author={S{\'e}bastien Goudenege and Carl Lebel and Nicolas Huot and Christine Dufour and Isao Fujii and Jean Gekas and Jo{\"e}l Rousseau and Jacques Pierre Tremblay},
  booktitle={Molecular therapy : the journal of the American Society of Gene Therapy},
  year={2012}
}
Human embryonic stem cells (hESCs) and human-induced pluripotent stem cells (hiPSCs) have an endless self-renewal capacity and can theoretically differentiate into all types of lineages. They thus represent an unlimited source of cells for therapies of regenerative diseases, such as Duchenne muscular dystrophy (DMD), and for tissue repair in specific medical fields. However, at the moment, the low number of efficient specific lineage differentiation protocols compromises their use in… CONTINUE READING

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