Myoarchitectural and functional alterations in rabbit external anal sphincter muscle following experimental surgical trauma.

@article{Rajasekaran2014MyoarchitecturalAF,
  title={Myoarchitectural and functional alterations in rabbit external anal sphincter muscle following experimental surgical trauma.},
  author={Mahadevan R Rajasekaran and Shantanu Sinha and Youngjin Seo and Mitra Salehi and Valmik Bhargava and Ravinder K Mittal},
  journal={American journal of physiology. Gastrointestinal and liver physiology},
  year={2014},
  volume={307 4},
  pages={
          G445-51
        }
}
Obstetrical trauma to external anal sphincter (EAS) is extremely common; however, its role in the development of anal incontinence is not clear. We examined the regenerative process and functional impact of experimental surgical trauma to EAS muscle in an animal model. Surgical myotomy, a craniocaudal incision extending along the entire length and thickness of the EAS, was performed in rabbits. Animals were allowed to recover, and anal pressures were recorded at weekly intervals for 12 wk using… CONTINUE READING
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